Detalhe da pesquisa
1.
Germline de novo variant F747S extends the phenotypic spectrum of CACNA1D Ca2+ channelopathies.
Hum Mol Genet
; 32(5): 847-859, 2023 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36208199
2.
CACNA1D-Related Channelopathies: From Hypertension to Autism.
Handb Exp Pharmacol
; 279: 183-225, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36592224
3.
Novel CACNA1A Variant p.Cys256Phe Disrupts Disulfide Bonds and Causes Spinocerebellar Ataxia.
Mov Disord
; 37(2): 401-404, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34647648
4.
STAC proteins associate to the IQ domain of CaV1.2 and inhibit calcium-dependent inactivation.
Proc Natl Acad Sci U S A
; 115(6): 1376-1381, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29363593
5.
De novo CACNA1D Ca2+ channelopathies: clinical phenotypes and molecular mechanism.
Pflugers Arch
; 472(7): 755-773, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32583268
6.
Correction to: De novo CACNA1D Ca2+ channelopathies: clinical phenotypes and molecular mechanism.
Pflugers Arch
; 472(8): 1105, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32666275
7.
RBP2 stabilizes slow Cav1.3 Ca2+ channel inactivation properties of cochlear inner hair cells.
Pflugers Arch
; 472(1): 3-25, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31848688
8.
Lower Affinity of Isradipine for L-Type Ca2+ Channels during Substantia Nigra Dopamine Neuron-Like Activity: Implications for Neuroprotection in Parkinson's Disease.
J Neurosci
; 37(28): 6761-6777, 2017 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28592699
9.
A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-gated CaV1.2 Calcium Channel Function.
J Biol Chem
; 290(34): 21086-21100, 2015 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26100638
10.
Novel protocol for multiple-dose oral administration of the L-type Ca2+ channel blocker isradipine in mice: A dose-finding pharmacokinetic study.
Channels (Austin)
; 18(1): 2335469, 2024 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38564754
11.
Pathogenicity of de novo CACNA1D Ca2+ channel variants predicted from sequence co-variation.
Eur J Hum Genet
; 2024 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38553610
12.
Cav 1.3-selective inhibitors of voltage-gated L-type Ca2+ channels: Fact or (still) fiction?
Br J Pharmacol
; 180(10): 1289-1303, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36788128
13.
The human channel gating-modifying A749G CACNA1D (Cav1.3) variant induces a neurodevelopmental syndrome-like phenotype in mice.
JCI Insight
; 8(20)2023 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37698939
14.
Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1.1.
J Gen Physiol
; 154(9)2022 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35349630
15.
Voltage-Gated Ca2+ Channels in Dopaminergic Substantia Nigra Neurons: Therapeutic Targets for Neuroprotection in Parkinson's Disease?
Front Synaptic Neurosci
; 13: 636103, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33716705
16.
Biophysical classification of a CACNA1D de novo mutation as a high-risk mutation for a severe neurodevelopmental disorder.
Mol Autism
; 11(1): 4, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31921405
17.
L-type calcium channels as drug targets in CNS disorders.
Channels (Austin)
; 10(1): 7-13, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26039257
18.
Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?
Curr Mol Pharmacol
; 8(2): 110-22, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25966690
19.
Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.
Nat Commun
; 5: 3897, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24941892